The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Sep. 22, 2014
Applicant:
University of South Carolina, Columbia, SC (US);
Inventors:
Campbell McInnes, Irmo, SC (US);
Shu Liu, West Columbia, SC (US);
Assignee:
UNIVERSITY OF SOUTH CAROLINA, Columbia, SC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); C07K 5/117 (2006.01); C07K 5/097 (2006.01); C07K 5/078 (2006.01); C07K 5/11 (2006.01); C07K 14/47 (2006.01); C07K 5/02 (2006.01); C07K 5/103 (2006.01); C07K 5/107 (2006.01); C07K 5/072 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1024 (2013.01); A61K 38/07 (2013.01); C07K 5/0202 (2013.01); C07K 5/06095 (2013.01); C07K 5/06139 (2013.01); C07K 5/0821 (2013.01); C07K 5/101 (2013.01); C07K 5/1016 (2013.01); C07K 5/1019 (2013.01); C07K 14/4738 (2013.01);
Abstract
Structural and functional analysis of peptide inhibitor binding to the cyclin D and cyclin A groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.