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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9376450 B1

PDFFull Text
Date of Patent:
Jun. 28, 2016

Filed:

May. 10, 2013

Heteroaryloxyheterocyclyl compounds as pde10 inhibitors

Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Jennifer R. Allen, Newbury Park, CA (US);

Daniel B. Horne, Simi Valley, CA (US);

Essa Hu Harrington, Camarillo, CA (US);

Matthew R. Kaller, Ventura, CA (US);

Holger Monenschein, San Diego, CA (US);

Thomas T. Nguyen, Newbury Park, CA (US);

Andreas Reichelt, Moorpark, CA (US);

Robert M. Rzasa, Ventura, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:

Elsa D. Lemoine

Primary Examiner:

Kahsay Habte

Int. Cl.
CPC ...
C07D 491/107 (2006.01); C07D 413/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 405/14 (2006.01); C07D 405/04 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01);
Abstract

Heteroaryloxyheterocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like.

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