The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Sep. 26, 2012
Amgen Inc., Thousand Oaks, CA (US);
Michael D. Bartberger, Sherman Oaks, CA (US);
Hilary Plake Beck, San Carlos, CA (US);
Xiaoqi Chen, Palo Alto, CA (US);
Richard Victor Connors, Pacifica, CA (US);
Jeffrey Deignan, San Francisco, CA (US);
Jason A. Duquette, South San Francisco, CA (US);
John Eksterowicz, San Francisco, CA (US);
Brian M. Fox, Brisbane, CA (US);
Jiasheng Fu, Foster City, CA (US);
Ana Gonzalez Buenrostro, San Mateo, CA (US);
Felix Gonzalez Lopez De Turiso, San Mateo, CA (US);
Darin J. Gustin, Half Moon Bay, CA (US);
Julie A. Heath, Orlinda, CA (US);
Michael G. Johnson, San Francisco, CA (US);
Frank Kayser, San Francisco, CA (US);
David John Kopecky, San Francisco, CA (US);
Yihong Li, Millbrae, CA (US);
Zhihong Li, Millbrae, CA (US);
Zhihua Ma, Foster City, CA (US);
Joel McIntosh, Pacifica, CA (US);
Julio C. Medina, San Carlos, CA (US);
Jeffrey Thomas Mihalic, San Francisco, CA (US);
Steven H. Olson, Millbrae, CA (US);
Yosup Rew, Foster City, CA (US);
Philip M. Roveto, San Francisco, CA (US);
Michael J. Schmitt, McLean, VA (US);
Daqing Sun, Foster City, CA (US);
Xiaodong Wang, Millbrae, CA (US);
Malgorzata Wanska, Oak Park, CA (US);
Christine Weathers, Katy, TX (US);
Xuelei Yan, Foster City, CA (US);
Amgen, Inc., Thousand Oaks, CA (US);
Abstract
The present invention provides MDM2 inhibitor compounds of Formula I or II, or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.