The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Oct. 15, 2013
Applicant:
Apotex Inc., Toronto, CA;
Inventors:
Probal Kanti Datta, Hamilton, CA;
Carlos Zetina-Rocha, Burnaby, CA;
Cameron L. McPhail, Brantford, CA;
Yajun Zhao, Brantford, CA;
Gamini Weeratunga, Ancaster, CA;
Assignee:
Apotex Inc., Toronto, Ontario, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07B 2200/13 (2013.01);
Abstract
Disclosed are solid forms of Nilotinib hydrochloride and methods of preparation of various crystalline solvates of Nilotinib HCl including benzyl alcohol, acetic acid, propylene glycol, and isopropanol. Nilotinib HCl is a tyrosine kinase inhibitor used for the treatment of drug resistant chronic myelogenous leukemia (CML).