The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2016

Filed:

Jun. 17, 2013
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Kirkland, Quebec, CA;

Inventors:

Andrew M. Haidle, Cambridge, MA (US);

Sandra Lee Knowles, Princeton, NJ (US);

Solomon D. Kattar, Arlington, MA (US);

Denis Deschenes, Lachine, CA;

Jason Burch, Redwood City, CA (US);

Joel Robichaud, Dollard-des-Ormeaux, CA;

Matthew Christopher, Brookline, MA (US);

Michael D. Altman, Needham, MA (US);

James P. Jewell, Newtown, MA (US);

Alan B. Northrup, Reading, VA (US);

Marc Blouin, Saint-Lazare, CA;

John Michael Ellis, Needham, MA (US);

Hua Zhou, Acton, MA (US);

Christian Fischer, Natick, MA (US);

Adam J. Schell, Decatur, GA (US);

Michael H. Reutershan, Brookline, MA (US);

Brandon M. Taoka, Hoboken, NJ (US);

Anthony Donofrio, Cambridge, MA (US);

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Merck Canada Inc., Kirkland, Quebec, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); A61K 31/506 (2006.01); A61K 31/505 (2006.01); A61K 45/06 (2006.01); A61K 31/5377 (2006.01); A61K 31/5383 (2006.01); A61K 31/551 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 491/107 (2006.01); C07D 491/113 (2006.01); C07D 498/04 (2006.01); C07D 491/08 (2006.01); C07D 409/14 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/5383 (2013.01); A61K 31/551 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 491/08 (2013.01); C07D 491/107 (2013.01); C07D 491/113 (2013.01); C07D 498/04 (2013.01);
Abstract

The invention provides certain substituted pyridines of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, C, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.


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