The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Apr. 15, 2015
Applicant:
Bayer Intellectual Property Gmbh, Monheim, DE;
Inventors:
Thomas Himmler, Odenthal, DE;
Lukas J. Goossen, Kaiserslautern, DE;
Felix Rudolphi, Schriesheim, DE;
Bingrui Song, Kaiserslautern, DE;
Assignee:
Bayer Intellectual Property GmbH, Monheim, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/24 (2006.01); C07C 67/343 (2006.01); C07C 319/20 (2006.01); C07C 253/30 (2006.01); C07C 201/12 (2006.01);
U.S. Cl.
CPC ...
C07D 333/24 (2013.01); C07C 67/343 (2013.01); C07C 201/12 (2013.01); C07C 253/30 (2013.01); C07C 319/20 (2013.01);
Abstract
The invention relates to a process for preparing aryl- and heteroarylacetic acids and derivatives thereof by reaction of aryl or heteroaryl halides with malonic diesters in the presence of a palladium catalyst, of one or more bases and optionally of a phase transfer catalyst. This process enables the preparation of a multitude of functionalized aryl- and heteroarylacetic acids and derivatives thereof, especially also the preparation of arylacetic acids with sterically demanding substituents.