The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Mar. 08, 2011
Romano Hoofman, Geel, BE;
Gerard Reuvers, Eindhoven, NL;
Franciscus Petrus Widdershoven, Eindhoven, NL;
Evelyne Gridelet, Omal, BE;
Marcus Henricus Van Kleef, Nijmegen, NL;
Romano Hoofman, Geel, BE;
Gerard Reuvers, Eindhoven, NL;
Franciscus Petrus Widdershoven, Eindhoven, NL;
Evelyne Gridelet, Omal, BE;
Marcus Henricus van Kleef, Nijmegen, NL;
NXP B.V., Eindhoven, NL;
Abstract
'Click-assembly' methods of assembling a sensor for sensing biologically-active molecules by measuring impedance changes, are disclosed, comprising supporting a bio-sensor on a carrier, the bio-sensor comprising an electronic component having at least one micro-electrode and at least one electrical contact, functionalizing the bio-sensor by physically or chemically coupling a bio-receptor molecule to each of the at least one micro-electrode, and subsequently assembling the bio-sensor with a micro-fluidic unit by means of a clamp which clamps the bio-sensor with the micro-fluidic unit, such that in use a fluid introduced into the micro-fluidic unit is able to contact the bio-receptor and is isolated from the electrical contact. The clamp may be a spring, and the method may avoid a requirement for sealing by chemical or thermal means and thereby avoid damaging the bio-receptor. Sensors which can be assembled according to such methods are also disclosed.