The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 28, 2016

Filed:

Apr. 11, 2008
Applicants:

Jinwoo Cheon, Seoul, KR;

Young-wook Jun, Gyeonggi-do, KR;

Jung-tak Jang, Seoul, KR;

Inventors:

Jinwoo Cheon, Seoul, KR;

Young-wook Jun, Gyeonggi-do, KR;

Jung-tak Jang, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/06 (2006.01); A61K 49/18 (2006.01); C01G 49/00 (2006.01); H01F 1/00 (2006.01); B82Y 5/00 (2011.01); B82Y 25/00 (2011.01);
U.S. Cl.
CPC ...
A61K 49/1875 (2013.01); A61K 49/1836 (2013.01); A61K 49/1863 (2013.01); A61K 49/1866 (2013.01); A61K 49/1869 (2013.01); C01G 49/009 (2013.01); C01G 49/0063 (2013.01); H01F 1/0054 (2013.01); B82Y 5/00 (2013.01); B82Y 25/00 (2013.01); C01P 2002/72 (2013.01); C01P 2002/85 (2013.01); C01P 2004/04 (2013.01); C01P 2006/42 (2013.01); Y10S 977/773 (2013.01); Y10S 977/93 (2013.01);
Abstract

The present invention relates to an MRI contrast agent that includes zinc-containing water-soluble metal oxide nanoparticles and has an improved contrast effect. The zinc-containing water-soluble metal oxide nanoparticles are characterized by addition of zinc to a matrix comprising the metal oxide nanoparticles or by substitution of metal in the matrix, resulting in the improved contrast effect of MRI. In addition, the zinc-containing metal oxide nanoparticles of the present invention include the MRI contrast agent t having hybrid structures of 'zinc-containing metal oxide nanoparticle—biologically/chemically active material' in which the nanoparticle is conjugated with a bioactive material such as proteins, antibodies, and chemical materials.


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