The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Apr. 25, 2014
Applicant:
The Rogosin Institute, Inc., New York, NY (US);
Inventors:
Lawrence Gazda, Xenia, OH (US);
Barry Smith, New York, NY (US);
Assignee:
THE ROGOSIN INSTITUTE, INC., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/09 (2010.01); A61K 33/24 (2006.01); C12N 5/095 (2010.01); G01N 33/543 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/437 (2006.01); A61K 31/519 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/437 (2013.01); A61K 31/519 (2013.01); A61K 31/704 (2013.01); C12N 5/0695 (2013.01); G01N 33/54313 (2013.01); C12N 2503/02 (2013.01); C12N 2533/76 (2013.01); G01N 2333/4703 (2013.01);
Abstract
The invention relates to the use of encapsulates of cancer cells, in agarose coated, agarose containing beads, for isolating chemotherapeutic resistant cells which have at least one stem cell property, such as expression of OCT4. The cells thus isolated are also a feature of the invention, as is a method for screening for potential therapeutic agents.