The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Oct. 15, 2014
Applicant:
Novo Nordisk A/s, Bagsvaerd, DK;
Inventors:
Henrik Oestergaard, Oelstykke, DK;
Prafull S. Gandhi, Ballerup, DK;
Ole Hvilsted Olsen, Broenshoej, DK;
Assignee:
NOVO NORDISK HEALTHCARE AG, Zurich, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/36 (2006.01); C07K 14/745 (2006.01); C12N 9/64 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/745 (2013.01); C12N 9/6437 (2013.01); C12Y 304/21021 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.