The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Sep. 19, 2014
Applicant:
Ajinomoto Co., Inc., Tokyo, JP;
Inventors:
Kunihiro Hirai, Kawasaki, JP;
Satoshi Katayama, Kawasaki, JP;
Takayoshi Torii, Kawasaki, JP;
Ryotaro Nakaya, Kawasaki, JP;
Daisuke Takahashi, Yokkaichi, JP;
Assignee:
AJINOMOTO CO., INC., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/02 (2006.01); C07H 21/00 (2006.01); C07H 1/00 (2006.01); C07H 19/06 (2006.01); C07H 19/073 (2006.01); C07H 19/173 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); C07H 1/00 (2013.01); C07H 1/02 (2013.01); C07H 19/06 (2013.01); C07H 19/073 (2013.01); C07H 19/173 (2013.01);
Abstract
The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3'-position.