The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2016

Filed:

Aug. 10, 2012
Applicants:

Yanmei Zhang, Guangdong, CN;

John Jeffrey Talley, Saint Louis, MO (US);

Mark G. Obukowicz, Three Lakes, WI (US);

Zhengchao Tu, Guangdong, CN;

Micky Tortorella, Guangdong, CN;

Yican Wang, Guangdong, CN;

Jianqi Liu, Guangdong, CN;

Yan Chen, Guangdong, CN;

Xiaorong Liu, Guangdong, CN;

Xin LU, Guangdong, CN;

Inventors:

Yanmei Zhang, Guangdong, CN;

John Jeffrey Talley, Saint Louis, MO (US);

Mark G. Obukowicz, Three Lakes, WI (US);

Zhengchao Tu, Guangdong, CN;

Micky Tortorella, Guangdong, CN;

Yican Wang, Guangdong, CN;

Jianqi Liu, Guangdong, CN;

Yan Chen, Guangdong, CN;

Xiaorong Liu, Guangdong, CN;

Xin Lu, Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/58 (2006.01);
U.S. Cl.
CPC ...
C07D 311/58 (2013.01);
Abstract

The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.


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