The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2016

Filed:

Jul. 27, 2012
Applicants:

Guangxin Xia, Shanghai, CN;

Jingkang Shen, Shanghai, CN;

Yongping Yu, Hangzhou, CN;

Wenteng Chen, Hangzhou, CN;

Chunchun Zhang, Shanghai, CN;

Yu Hao, Shanghai, CN;

Jing Zhang, Shanghai, CN;

Bojun LI, Shanghai, CN;

Xuejun Liu, Shanghai, CN;

Inventors:

Guangxin Xia, Shanghai, CN;

Jingkang Shen, Shanghai, CN;

Yongping Yu, Hangzhou, CN;

Wenteng Chen, Hangzhou, CN;

Chunchun Zhang, Shanghai, CN;

Yu Hao, Shanghai, CN;

Jing Zhang, Shanghai, CN;

Bojun Li, Shanghai, CN;

Xuejun Liu, Shanghai, CN;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/94 (2006.01); A61K 31/517 (2006.01); A61P 35/00 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 239/94 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01);
Abstract

Disclosed are as represented by Formula (I) a quinazoline derivative and a pharmaceutical acceptable salt thereof, or, an enantiomer, a non-enantiomer, a tautomer, a racemate, a solvate, a metabolic precursor, or a prodrug of both. Also disclosed are a preparation method therefor, an intermediate, a pharmaceutical composition having the quinazoline derivative, and an application thereof. The quinazoline derivative of the present invention is provided with improved anti-tumor activity.


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