The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Sep. 22, 2014
Applicant:
Augusta University Research Institute, Inc., Augusta, GA (US);
Inventors:
Cargill H. Alleyne, Jr., Martinez, GA (US);
Krishnan M. Dhandapani, Evans, GA (US);
Ken Wen, Shanghai, CN;
MingLiang Ma, Shanghai, CN;
WenJing Hu, Shanghai, CN;
Assignees:
Augusta University Research Institute, Inc., Augusta, GA (US);
East China Normal University, Shanghai, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/248 (2006.01); C07C 49/235 (2006.01); C07C 49/255 (2006.01); C07C 59/90 (2006.01); C07C 69/738 (2006.01);
U.S. Cl.
CPC ...
C07C 49/248 (2013.01); C07C 49/235 (2013.01); C07C 49/255 (2013.01); C07C 59/90 (2013.01); C07C 69/738 (2013.01);
Abstract
Disclosed herein are compounds, compositions and methods for preventing and treating diseases such as intracerebral hemorrhage, cancer, or conditions associated with damaged cells, activated lymphocytes, or microbial products. The disclosed compounds are curcumin analogs. The curcumin analogs possess anti-inflammatory and antioxidant properties, which in part, reduce AP-1 and NF-κB activity.