The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Nov. 09, 2015
Applicant:
Novo Nordisk Healthcare Ag, Zurich, CH;
Inventors:
Henrik Oestergaard, Oelstykke, DK;
Prafull S. Gandhi, Ballerup, DK;
Ole Hvilsted Olsen, Broenshoej, DK;
Carsten Behrens, Koebenhavn N, DK;
Paul L. DeAngelis, Edmond, OK (US);
Friedrich Michael Haller, Norman, OK (US);
Assignee:
NOVO NORDISK HEALTHCARE AG, Zurich, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/36 (2006.01); C07K 14/745 (2006.01); A61P 7/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/4823 (2013.01); A61K 38/36 (2013.01);
Abstract
The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.