The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Feb. 11, 2015
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventor:
Gregory Bix, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/39 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 38/39 (2013.01);
Abstract
The presently-disclosed subject matter provides methods for preventing ischemia in a cell, treating ischemia in a subject, and preventing an infarction in a subject that utilize α5β1 integrin inhibitor. In some instances, α5β1 integrin inhibitor is administered to a subject prior to, during, or after the onset of ischemia to treat the ischemia and/or prevent infarction. In some instances the present methods prevent the occurrence of an infarction. In some instances the present methods restores perfusion to organs and tissues.