The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Oct. 17, 2014
Applicant:
Inotek Pharmaceuticals Corporation, Lexington, MA (US);
Inventors:
Norman N. Kim, Westford, MA (US);
William K. McVicar, Sudbury, MA (US);
Thomas G. McCauley, Cambridge, MA (US);
Rudolf A. Baumgartner, Sudbury, MA (US);
Assignee:
Inotek Pharmaceuticals Corporation, Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A61K 31/7076 (2006.01); A61K 9/00 (2006.01); A61K 31/165 (2006.01); A61K 31/19 (2006.01); A61K 31/216 (2006.01); A61K 45/06 (2006.01); C07H 19/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 9/0048 (2013.01); A61K 31/165 (2013.01); A61K 31/19 (2013.01); A61K 31/216 (2013.01); A61K 45/06 (2013.01); C07H 19/16 (2013.01);
Abstract
The present invention is directed to a composition or a kit comprising a combination of a prostaglandin analog and an adenosine receptor Aagonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. In some embodiments, the adenosine receptor Aagonist is Compound A, ((2R,3S,4R,5R)-5-(6 -(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate, having the structure,