The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Jun. 19, 2015
Applicant:
Oncodesign S.a., Dijon, FR;
Inventors:
Petra Marcella Francoise Blom, Destelbergen, BE;
Jan Marie Cyriel Jozef Hoflack, Malle, BE;
Assignee:
Oncodesign S.A., Dijon, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/504 (2006.01); A61K 31/505 (2006.01); C07D 471/22 (2006.01); C07D 487/18 (2006.01); C07D 498/18 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/5377 (2013.01); C07D 471/22 (2013.01); C07D 487/18 (2013.01); C07D 498/18 (2013.01);
Abstract
The present invention relates to macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of FLT3 (FMS-Related Tyrosine kinase 3). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.