The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Mar. 07, 2014
Applicants:
Califia Bio, Inc., San Diego, CA (US);
University of Rochester, Rochester, NY (US);
Inventors:
Val S. Goodfellow, Encinitas, CA (US);
Thong X. Nguyen, San Diego, CA (US);
Satheesh B. Ravula, San Diego, CA (US);
Harris A. Gelbard, Pittsford, NY (US);
Assignees:
CALIFIA BIO, INC., San Diego, CA (US);
UNIVERSITY OF ROCHESTER, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01); C07D 513/04 (2006.01); A61K 31/427 (2006.01); A61K 31/4402 (2006.01); A61K 31/513 (2006.01); A61K 31/536 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5025 (2013.01); A61K 31/427 (2013.01); A61K 31/4402 (2013.01); A61K 31/513 (2013.01); A61K 31/536 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); C07D 513/04 (2013.01);
Abstract
Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.