The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2016
Filed:
Feb. 22, 2013
Applicant:
Fate Therapeutics, Inc., San Diego, CA (US);
Inventors:
Robert Scott Thies, San Diego, CA (US);
Francine Farouz, San Carlos, CA (US);
Zhiyong Wang, San Diego, CA (US);
Chin-Chun Jean Lu, San Diego, CA (US);
Assignee:
Fate Therapeutics, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/38 (2006.01); A61K 31/40 (2006.01); A61K 31/475 (2006.01); A61K 31/404 (2006.01); A61K 31/506 (2006.01); A61K 31/55 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/475 (2013.01); A61K 9/0046 (2013.01); A61K 31/404 (2013.01); A61K 31/506 (2013.01); A61K 31/55 (2013.01);
Abstract
The invention is directed, in part, to compositions comprising small molecule compounds to treat or prevent hearing loss. Compositions of the present invention also promote sensory hair cell regeneration. Particular compositions comprise ellipticine derivatives, and optionally one or more small molecules that increase Atoh1 expression or activity, and optionally one or more growth factors.