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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9370481 B1

PDFFull Text
Date of Patent:
Jun. 21, 2016

Filed:

Apr. 19, 2011

Compositions and methods for inhibiting gastric acid secretion

Applicants:

Aleksey Kostadinov, Rehovot, IL;

David Ayelet, Negev, IL;

Sabina Glozman, Rehovot, IL;

Tal Atarot, Tel Mond, IL;

Inventors:

Aleksey Kostadinov, Rehovot, IL;

David Ayelet, Negev, IL;

Sabina Glozman, Rehovot, IL;

Tal Atarot, Tel Mond, IL;

Assignee:

Vecta, Ltd., Ramat Gan, IL;

Attorneys:

Cooley LLP

Ivor R. Elrifi

Christina K. Stock

Primary Examiner:

Brian-Yong Kwon

Assistant Examiner:

Miriam A Levin

Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 9/00 (2006.01); A61P 1/04 (2006.01); A61K 31/4439 (2006.01); A61K 31/19 (2006.01); A61K 31/194 (2006.01); A61K 31/215 (2006.01); A61K 31/225 (2006.01); A61K 31/7048 (2006.01); A61K 31/197 (2006.01); A61K 31/166 (2006.01); A61K 31/454 (2006.01); A61K 31/4468 (2006.01); A61K 31/4045 (2006.01); A61K 38/31 (2006.01); A61K 9/20 (2006.01); A61K 9/50 (2006.01); A61K 31/191 (2006.01); A61K 45/06 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0004 (2013.01); A61K 9/0019 (2013.01); A61K 9/2081 (2013.01); A61K 9/4808 (2013.01); A61K 9/5042 (2013.01); A61K 9/5047 (2013.01); A61K 9/5084 (2013.01); A61K 31/19 (2013.01); A61K 31/191 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); A61K 47/12 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present invention is related to novel oral compositions comprising an irreversible gastric H/K-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more small carboxylic acid molecules as parietal cell activators in the gastric lumen. Unexpectedly, the compositions of the present invention are capable of enhancing the anti-acid activity of PPI in the stomach. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.

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