The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

Jun. 16, 2010
Applicants:

Puiying Annie Mak, San Diego, CA (US);

George Santos, Wayland, MA (US);

Jeffrey Eugene Janes, San Diego, CA (US);

John J. Donnelly, Moraga, CA (US);

Inventors:

Puiying Annie Mak, San Diego, CA (US);

George Santos, Wayland, MA (US);

Jeffrey Eugene Janes, San Diego, CA (US);

John J. Donnelly, Moraga, CA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); A01N 63/00 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01);
Abstract

The disclosure provides methods and kits for performing automated high-throughput assays to measure bactericidal activity in samples, such as plasma or sera from vaccinated subjects to evaluate the efficacy of vaccines against bacterial pathogens. The method combines obligatory linear-range data analysis, plate sealing and liquid volume handling for all assay steps to provide an automated, high-throughput measurement of bactericidal activity with favorable inter-assay and inter-operator variability.


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