The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Oct. 02, 2012
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Martina Hueller, Achmuehle, DE;
Dietmar Reusch, Munich, DE;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 16/28 (2006.01); C07K 16/34 (2006.01); C12P 21/00 (2006.01); C07K 16/00 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C12P 21/005 (2013.01); C07K 16/00 (2013.01); C07K 16/2803 (2013.01); C07K 16/2866 (2013.01); C07K 16/32 (2013.01); C07K 2317/41 (2013.01);
Abstract
The current invention comprises a method for producing an immunoglobulin or immunoglobulin fragment or immunoglobulin fusion with G1 glycostructure comprising incubating with a galactosyltransferase, a sialyltransferase, a beta-1,4-galactosidase and a sialidase, whereby the galactosyltransferase is added in more than one aliquot during the incubating.