The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
May. 11, 2009
Applicants:
Riaan Den Haan, Durbanville, ZA;
Emile Van Zyl, Stellenbosch, ZA;
Danie Lagrange, Durbanville, ZA;
Inventors:
Assignee:
Stellenbosch University, Stellenbosch, ZA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12N 15/00 (2006.01); C12N 9/42 (2006.01); C12P 7/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2437 (2013.01); C12P 7/10 (2013.01); C12Y 302/01091 (2013.01); Y02E 50/16 (2013.01); Y02P 20/52 (2015.11);
Abstract
The present invention provides for heterologous expression of polypeptides encoded by wild-type and codon-optimized variants of cbh1 and/or cbh2 from the fungal organisms(),(),(), and() in host cells, such as the yeast. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed cellobiohydrolases. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.