The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Mar. 01, 2012
Daniel Offen, Kfar HaRoe, IL;
Michal Dadon-nachum, Kfar-Saba, IL;
Tali Ben-zur, RaAnana, IL;
Eldad Melamed, Tel-Aviv, IL;
David Yaffe, Givat Brenner, IL;
Daniel Offen, Kfar HaRoe, IL;
Michal Dadon-Nachum, Kfar-Saba, IL;
Tali Ben-Zur, RaAnana, IL;
Eldad Melamed, Tel-Aviv, IL;
David Yaffe, Givat Brenner, IL;
Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;
Yeda Research and Development Co., Ltd., Rehovot, IL;
Abstract
An isolated muscle progenitor cell being MyoD positive, CD34 negative and CD45 negative is disclosed. The muscle progenitor cell is genetically modified to express at least one neurotrophic factor. In addition, cell populations are disclosed, comprising at least four subpopulations of muscle cells each being genetically modified to express a different neurotrophic factor, wherein said neurotrophic factor is selected from the group consisting of glial derived neurotrophic factor (GDNF), insulin growth factor (IGF-1), vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). Uses of the cell populations are also disclosed.