The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
May. 28, 2013
Applicant:
Oncolytics Biotech Inc., Calgary, CA;
Inventors:
Assignee:
Oncolytics Biotech Inc., Calgary, Alberta, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61K 35/768 (2015.01); C12N 5/078 (2010.01); A61K 35/28 (2015.01); C12N 15/64 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0634 (2013.01); A61K 35/28 (2013.01); A61K 35/761 (2013.01); A61K 35/768 (2013.01); C12N 2720/12032 (2013.01);
Abstract
The present invention relates to a method for removing neoplastic cells from a mixed cellular composition, which is outside of a living organism, by using a virus which selectively infect and kill neoplastic cell. A variety of viruses can be used in this method to remove neoplastic cells for different purposes, for example, to purge hematopoietic stem cells prior to transplantation. Also provided are compositions prepared according to this method, and kits comprising a combination of viruses which are useful in this invention.