The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

Sep. 19, 2012
Applicants:

Stefan Franz Thomas Weiss, Johannesburg, ZA;

Katarina Jovanovic, Edenvale, ZA;

Danielle Gonsavles, Johannesburg, ZA;

Bianca Da Costa Dias, Johannesburg, ZA;

Stefan Knackmuss, Plankstadt, DE;

Uwe Reusch, Maikammer, DE;

Melvyn Little, St. Peter-Ording, DE;

Marc Saul Weinberg, Midrand, ZA;

Inventors:

Stefan Franz Thomas Weiss, Johannesburg, ZA;

Katarina Jovanovic, Edenvale, ZA;

Danielle Gonsavles, Johannesburg, ZA;

Bianca Da Costa Dias, Johannesburg, ZA;

Stefan Knackmuss, Plankstadt, DE;

Uwe Reusch, Maikammer, DE;

Melvyn Little, St. Peter-Ording, DE;

Marc Saul Weinberg, Midrand, ZA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 31/7105 (2006.01); A61K 39/395 (2006.01); C12N 15/113 (2010.01); C07K 16/26 (2006.01);
U.S. Cl.
CPC ...
C07K 16/26 (2013.01); A61K 31/7105 (2013.01); A61K 39/3955 (2013.01); C12N 15/1138 (2013.01); C07K 2317/76 (2013.01);
Abstract

The invention relates to a method of modulating concentration of Alzheimer's Disease (AD) relevant proteins amyloid precursor protein (APP), beta (β) and gamma (γ) secretases and amyloid beta peptide (Aβ), and also relates to a method of reducing Aβ shedding. Furthermore, this invention extends to a compound for use in the treatment of AD, and also to a method of treating AD.


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