The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
May. 25, 2012
Donald E. Champagne, Athens, GA (US);
Hitoshi Tsujimoto, Bellefonte, PA (US);
Ivo Francischetti, Bethesda, MD (US);
Michael R. Strand, Athens, GA (US);
Michail Kotsyfakis, Ceske Budejovice, CZ;
Donald E. Champagne, Athens, GA (US);
Hitoshi Tsujimoto, Bellefonte, PA (US);
Ivo Francischetti, Bethesda, MD (US);
Michael R. Strand, Athens, GA (US);
Michail Kotsyfakis, Ceske Budejovice, CZ;
University of Georgia Research Foundation, Inc., Athens, GA (US);
The United States of America, as represented by the Secretary of the Dept. of Health & Human Services, Washington, DC (US);
Biology Centre CAS, v.v.i., , CZ;
Abstract
The present invention includes a novel protein, also referred to herein as simukunin, that inhibits the function of several physiologically important enzymes. Simukunin is a potent inhibitor of the blood coagulation cascade, inhibiting Factor Xa and functioning as an efficient anticoagulant. Simukunin also inhibits the serine proteases elastase and cathepsin and demonstrates anti-inflammatory properties. Also included are methods of making and using simukunin.