The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Apr. 17, 2012
Applicants:
Nahoko Kobayashi, Tsukuba, JP;
Tetsuhiko Yoshida, Tsukuba, JP;
Mikio Niwa, Tsukuba, JP;
Inventors:
Assignee:
TOAGOSEI CO. LTD., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 7/06 (2006.01); C07K 14/715 (2006.01); C07K 14/47 (2006.01); A61K 35/12 (2015.01); A61K 38/10 (2006.01); A61K 35/28 (2015.01); A61K 35/26 (2015.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 7/06 (2013.01); C07K 14/4705 (2013.01); C07K 14/7151 (2013.01); A61K 35/26 (2013.01); A61K 35/28 (2013.01); A61K 38/10 (2013.01); A61K 2035/126 (2013.01); C07K 2319/09 (2013.01);
Abstract
This invention provides a TNFR2 expression-inducing composition including as an active ingredient a peptide having TNFR2 expression-inducing activity, and a method for producing cells that express TNFR2 selectively by use of the composition. The cell production method provided by this invention includes: culturing at least one species of cells capable of expressing TNF receptor 2, and supplying the cells with a synthetic peptide consisting of a nuclear localization signal sequence (NLS) or a nucleolar localization signal sequence (NoLS) to enhance TNFR2 expression in the cells.