The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

May. 22, 2013
Applicants:

Simona Cotesta, Basel, CH;

Pascal Furet, Thann, FR;

Vito Guagnano, Basel, CH;

Philipp Holzer, Sissach, CH;

Joerg Kallen, Basel, CH;

Robert Mah, Muttenz, CH;

Keiichi Masuya, Basel, CH;

Achim Schlapbach, Lorrach, DE;

Stefan Stutz, Basel, CH;

Andrea Vaupel, Riehen, CH;

Inventors:

Simona Cotesta, Basel, CH;

Pascal Furet, Thann, FR;

Vito Guagnano, Basel, CH;

Philipp Holzer, Sissach, CH;

Joerg Kallen, Basel, CH;

Robert Mah, Muttenz, CH;

Keiichi Masuya, Basel, CH;

Achim Schlapbach, Lorrach, DE;

Stefan Stutz, Basel, CH;

Andrea Vaupel, Riehen, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/407 (2006.01); A61K 31/44 (2006.01); A61K 31/5377 (2006.01); A61K 31/506 (2006.01); A61K 31/41 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/407 (2013.01); A61K 31/41 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention relates to compounds of formula (I): as described herein, pharmaceutical preparations comprising such compounds, uses and methods of use for such compounds in the treatment of a disorder or a disease mediated by the activity of MDM2 and/or MDM4, and combinations comprising such compounds.


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