The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Jul. 26, 2012
Applicants:
Hui Zhang, Jinan, CN;
Yanyan Dong, Jinan, CN;
Inventors:
Hui Zhang, Jinan, CN;
Yanyan Dong, Jinan, CN;
Assignee:
KBP Biosciences Co., Ltd., Jinan, Shandong Province, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/26 (2006.01); C07D 221/20 (2006.01); C07D 205/04 (2006.01); C07D 205/12 (2006.01); C07D 209/52 (2006.01); C07D 209/54 (2006.01); A61K 31/65 (2006.01); C07C 231/12 (2006.01); C07D 221/22 (2006.01); C07D 305/06 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07C 237/26 (2013.01); A61K 31/65 (2013.01); C07C 231/12 (2013.01); C07D 205/04 (2013.01); C07D 205/12 (2013.01); C07D 209/52 (2013.01); C07D 209/54 (2013.01); C07D 221/20 (2013.01); C07D 221/22 (2013.01); C07D 305/06 (2013.01); C07D 491/107 (2013.01); C07C 2101/04 (2013.01); C07C 2102/40 (2013.01); C07C 2103/46 (2013.01); C07C 2103/94 (2013.01);
Abstract
The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as well as a method for preparing these compounds and a pharmaceutical composition comprising the same. The present invention relates also to a use of these compounds in the preparation of a medicament for the treatment and/or prophylaxis of tetracycline drug-sensitive disease. wherein, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, Rand Rare each independently as defined in the description.