The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Mar. 19, 2015
Centro DE Ingenieria Genetica Y Biotecnologia, Ciudad de la Habana, CU;
Jesus Arturo Junco Barranco, Camaguey, CU;
Osvaldo Reyes Acosta, Ciudad de la Habana, CU;
Eddy Emilio Bover Fuentes, Camaguey, CU;
Franklin Fuentes Aguilar, Camaguey, CU;
Eulogio Pimentel Vazquez, Camaguey, CU;
Roberto Basulto Baker, Camaguey, CU;
Gerardo Enrique Guillen Nieto, Ciudad Habana, CU;
Yovisleidys Lopez Saez, Camaguey, CU;
Hilda Elisa Garay Perez, Ciudad Habana, CU;
Lesvia Calzada Aguilera, Camaguey, CU;
Maria Castro Santana, Camaguey, CU;
Niurka Oneysi Arteaga More, Camaguey, CU;
Luis Alberto Aguero Barrocal, Camaguey, CU;
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA, Ciudad de la Habana, CU;
Abstract
A pharmaceutical composition using natural gonadotropin—releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or carboxyl extremes to a carrier molecule; in one case by its carboxyl extreme and in the other case by the amino terminal extreme, thus eliciting a faster and more potent immunological response against the endogenous GnRH hormone. This finally leads to the ablation of the GnRH and consequently of the rest of the involved hormones in the stream GnRH/LH-FSH/Testosterone-(estrogens). An advantage of this formulation consists on facilitating the exposition to the immune system of a greater number of epitopes of the GnRH or its mimetics, minimizing thus the steric hindrance produced by the carriers. This invention has a direct application in the castration of pets and animals of economic interest, in the control of human fertility as well as in the treatment of hormone-sensitive tumors, such as that of the prostate, the breast, ovary, the endometry, testicles, hypophysis, salivary glands and other kinds of human tumors.