The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

Mar. 20, 2014
Applicant:

Lucas Meyer Cosmetics Canada Inc., Quebec, CA;

Inventor:

Benoit Cyr, St. Augustin de Desmaures, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/704 (2006.01); A61K 36/185 (2006.01); A61K 8/97 (2006.01); A61K 36/00 (2006.01); A61Q 19/08 (2006.01); C12N 9/99 (2006.01);
U.S. Cl.
CPC ...
A61K 36/185 (2013.01); A61K 8/97 (2013.01); A61K 36/00 (2013.01); A61K 36/704 (2013.01); A61Q 19/08 (2013.01); C12N 9/99 (2013.01); A61K 2800/782 (2013.01);
Abstract

Provided is a plant derived extract including inhibitory activity against one or more extracellular proteases which degrade human tissue matrix. Moreover, the amount of inhibitory activity in an extract can be increased by stressing the plant prior to forming an extract. These extracts are each prepared by a process and demonstrate the ability to inhibit one or more extracellular proteases which degrade human tissue matrix. Libraries of extracts can be prepared from stressed and non-stressed plants, where each of the extracts demonstrate inhibitory activity against on or more extracellular protease inhibitors. Alternatively, semi-purified and purified inhibitory compounds can be isolated from the extracts. In one aspect, these extracts with inhibitory activity can be used during protein purification to minimize degradation due to extracellular proteases.


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