The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Mar. 28, 2012
Yongzhang Luo, Beijing, CN;
Yang Chen, Beijing, CN;
Yan Fu, Beijing, CN;
Lin Jia, Beijing, CN;
Guodong Chang, Beijing, CN;
Yongzhang Luo, Beijing, CN;
Yang Chen, Beijing, CN;
Yan Fu, Beijing, CN;
Lin Jia, Beijing, CN;
Guodong Chang, Beijing, CN;
Tsinghua University, Beijing, CN;
Beijing Protgen LTD., Beijing, CN;
Abstract
The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic efficacy of a therapeutic agent by increasing the uptake of the therapeutic agent by target cells, and in particular relates to a pharmaceutical composition comprising a regulating agent of lipid raft/caveolae-dependent endocytic pathway and some therapeutic agents, such as anti-tumor agents. The invention also relates to a method for screening a regulating agent of lipid raft/caveolae-dependent endocytic pathway capable of enhancing the therapeutic efficacy of anti-tumor agents.