The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Feb. 13, 2013
Industry-academic Cooperation Foundation, Yonsei University, Seoul, KR;
Young Min Kim, Seoul, KR;
Seung Jung Han, Seoul, KR;
Tae Gwon Oh, Seoul, KR;
Sae Woong Park, Seoul, KR;
Sang Nae Cho, Seoul, KR;
Mi Young Hahn, Seoul, KR;
Jee Hee Suh, Daejeon, KR;
Kyu Yang Yi, Daejeon, KR;
Abstract
The present invention relates to a pharmaceutical composition for preventing or treating tuberculosis, comprising: (a) a pharmaceutically effective amount of a compound represented by the following chemical formula 1; and (b) a pharmaceutically acceptable carrier. Chemical formula 1 The compound contained as an active ingredient of the present invention inhibits the expression and activity of CO-DH in tubercleso as to effectively block the detoxification of carbon monoxide, which is an important survival factor of tubercle, and is safe for the human body since the compound targets CO-DH which does not exist in the human body. In addition, the compound creates a synergistic effect when combined with a conventional tuberculostatic drug, and thus can be more effective for treating tuberculosis.