The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

Jun. 14, 2012
Applicants:

Saburo Sakoda, Hyogo, JP;

Kei Fukada, Osaka, JP;

Inventors:

Saburo Sakoda, Hyogo, JP;

Kei Fukada, Osaka, JP;

Assignee:

Lundbeck NA Ltd., Wilmington, DE (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/122 (2006.01); A61K 31/275 (2006.01); A61K 31/165 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/122 (2013.01); A61K 31/165 (2013.01); A61K 31/275 (2013.01); A61K 45/06 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present disclosure relates to a more effective therapeutic agent capable of improving and treating the axial symptoms (particularly freezing of gait symptom) of patients with Parkinson's disease. Such symptoms in patients with Parkinson's disease can be improved and treated by using L-threo-3,4-dihydroxy-phenylserine (DOPS) and a COMT inhibitor in combination together, optionally with an L-DOPA preparation as well. As a result, the axial symptoms difficult to improve with conventional L-DOPA preparations can be treated, and a therapeutic agent and a treatment method are provided for the axial symptoms of patients with Parkinson's disease, particularly those suffering from the disease at a moderate level or higher.


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Sakoda, Saburo. (2016). Method of treating postural reflex abnormality caused by parkinson's disease (U.S. Patent No. 9364453). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9364453

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