The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2016
Filed:
Jun. 09, 2011
Applicants:
Martin J. Sadowski, New York, NY (US);
Kent Kirshenbaum, New York, NY (US);
Inventors:
Martin J. Sadowski, New York, NY (US);
Kent Kirshenbaum, New York, NY (US);
Assignee:
New York University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/12 (2006.01); A61K 38/16 (2006.01); C07K 7/06 (2006.01); C07K 7/64 (2006.01); C07K 14/00 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
A61K 31/135 (2013.01); A61K 38/08 (2013.01); A61K 38/12 (2013.01); A61K 38/16 (2013.01); C07K 7/06 (2013.01); C07K 7/64 (2013.01); C07K 14/00 (2013.01);
Abstract
Novel peptide/peptoid oligomers are disclosed that have a formula represented by the following formula Ia or Ib: The peptide/peptoid oligomers demonstrate the ability to inhibit fibrillization and oligomerization of Aβ and may be prepared as pharmaceutical compositions and used for the prevention or treatment of a variety of conditions in mammals, including humans, associated with Aβ oligomerization. The present peptidomimetic oligomers are particularly valuable for the treatment of subjects with AD.