The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2016

Filed:

Mar. 05, 2009
Applicants:

Arnaud Beduneau, Lincoln, NE (US);

Howard Gendelman, Omaha, NE (US);

Barrett Rabinow, Skokie, IL (US);

Jane Werling, Arlington Heights, IL (US);

Inventors:

Arnaud Beduneau, Lincoln, NE (US);

Howard Gendelman, Omaha, NE (US);

Barrett Rabinow, Skokie, IL (US);

Jane Werling, Arlington Heights, IL (US);

Assignees:

BAXTER INTERNATIONAL, INC., Deerfield, IL (US);

BAXTER HEALTHCARE SA, Glattpark (Opfikon), CH;

BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA, Lincoln, NE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/337 (2006.01); A61K 9/51 (2006.01); A61K 9/14 (2006.01); A61K 47/48 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5115 (2013.01); A61K 9/146 (2013.01); A61K 9/5161 (2013.01); A61K 9/5169 (2013.01); A61K 31/337 (2013.01); A61K 47/48561 (2013.01); A61K 47/48853 (2013.01); A61K 47/48861 (2013.01); C07K 16/283 (2013.01); Y10T 428/2991 (2015.01);
Abstract

The present disclosure is directed to surface-modified particles and to methods of making and using the same. The surface-modified particles comprise a particle core and a coating associated with the particle core, wherein the particle core comprises an active agent, the coating comprises an opsonin, and the surface-modified particle has an average size from about 1 nm to about 2,000 nm.


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