The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

May. 24, 2013
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Ji Yi, Chicago, IL (US);

Vadim Backman, Chicago, IL (US);

Qing Wei, Evanston, IL (US);

Hao F. Zhang, Deerfield, IL (US);

Assignee:

NORTHWESTERN UNIVERSITY, Evanston, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G02B 21/06 (2006.01); G02B 21/00 (2006.01); G01N 21/64 (2006.01); G01B 9/02 (2006.01); G01N 21/45 (2006.01); G01N 21/47 (2006.01); G01N 21/17 (2006.01);
U.S. Cl.
CPC ...
G02B 21/0032 (2013.01); G01B 9/02014 (2013.01); G01B 9/02044 (2013.01); G01B 9/02069 (2013.01); G01B 9/02091 (2013.01); G01N 21/45 (2013.01); G01N 21/4795 (2013.01); G01N 21/64 (2013.01); G01N 21/6458 (2013.01); G01N 2021/1787 (2013.01); G01N 2021/456 (2013.01); G01N 2201/067 (2013.01); G01N 2201/0691 (2013.01);
Abstract

Certain examples provide a structured illumination microscopy system. The example system includes a laser source to generate excitation illumination directed toward a target. The example system includes a modulator to modulate the excitation illumination temporally in a controllable spatial pattern to be constructed on the target object to provide sub-diffractional resolution in a lateral direction with respect to the target. The example system includes two synchronized laser scanning mirror units in confocal arrangement, the laser scanning units to be synchronized and controlled by a computing device, a first of the scanning mirror units to receive the modulated excitation illumination and project the modulated excitation illumination on the target object and a second of the scanning mirror units to receive emission fluorescence from the target and project the emission fluorescence. The example system includes a detector to collect emission fluorescence from the target via the second of the scanning mirror units.


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