The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Jun. 24, 2013
Centre Hospitalier Régional Universitaire DE Lille, Lille, FR;
Université DE Droit ET Santé DE Lille, Lille, FR;
Université Sciences Technologies Lille, Villeneuve d'Ascq, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Daniel Poulain, Templeuve, FR;
Boualem Sendid, Loos, FR;
Yann Guerardel, Ronchin, FR;
Nadine Francois, Lille, FR;
Centre Hospitalier Regional Universitaire De Lille, Lille, FR;
Universite De Droit Et Sante De Lille, Lille, FR;
Universite Sciences Technologies Lille, Villeneuve d'Ascq, FR;
Centre National De La Recherche Scientifique, Paris, FR;
Abstract
A method for the in vitro diagnosis of an invasive fungal infection by MALDI-TOF mass spectrometry. The method involves, providing a liquid biological sample from a mammal, said biological sample containing, in particular, proteins and/or lipids and/or salts and/or polysaccharides and/or oligosaccharides and/or monosaccharides capable of forming complexes with said proteins and/or lipids and/or salts; treating said sample with biological liquid so as to extract said polysaccharides and/or oligosaccharides and/or monosaccharides; determining, by MALDI-TOF mass spectrometry, whether or not there is present among said extracted polysaccharides, oligosaccharides and/or monosaccharides, at least one given compound of interest coming from said fungal microorganism and chosen from polysaccharides, oligosaccharides and monosaccharides; and deducing, if said given compound of interest is present in said sample, that said mammal is suffering from an invasive fungal infection.