The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Dec. 13, 2013
Applicant:

Dh Technologies Development Pte. Ltd., Singapore, SG;

Inventors:

John L. Campbell, Milton, CA;

Yves Leblanc, Newmarket, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/92 (2006.01); G01N 27/62 (2006.01); H01J 49/00 (2006.01); H01J 49/04 (2006.01);
U.S. Cl.
CPC ...
G01N 27/624 (2013.01); G01N 27/622 (2013.01); G01N 33/92 (2013.01); H01J 49/0031 (2013.01); H01J 49/0422 (2013.01); G01N 2458/15 (2013.01); Y10T 436/24 (2015.01);
Abstract

A method for analyzing a sample that contains a plurality of lipid isomers is described that involves forming one or more lipid metal ion adducts and transporting the one or more lipid metal ion adducts through a differential mobility spectrometer to cause separation of the one or more lipid metal ion adducts from each other. The lipid isomers can be chosen, for example, from fatty acids, glycerolipids, glycerophospholipids, sphingolipids, saccharolipids, polyketides, sterol lipids, and prenol lipids. Particular examples include phosphatidylcholine regioisomers such as 1-palmatoyl-2-oleoyl-sn-phosphatidylcholine (POPC) and 1-oleoyl-2-palmatoyl-sn-phosphatidylcholine and triacylglycerols containing palmetic and oleic acid groups. The metal chosen can include a cationization reagent that contains sodium, potassium, silver or lithium.


Find Patent Forward Citations

Loading…