The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
May. 21, 2013
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Vincent P. Mauro, La Jolla, CA (US);
Luke Burman, La Jolla, CA (US);
Gerald M. Edelman, La Jolla, CA (US);
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/85 (2006.01); C12N 15/67 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 15/67 (2013.01);
Abstract
Provided herein is a synthetic or isolated polynucleotide encoding a mammalian 18S rRNA that is resistant to pactamycin. The pactamycin-resistance is conferred by one or more single residue substitutions in the 18S rRNA sequence; a fragment thereof harboring said substitutions; a complementary sequence thereto; or a substantially identical sequence of the foregoing. Related systems, methods and kits are also described.