The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Jan. 14, 2013
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Jian Wu, Lynnwood, WA (US);
Nicole Le, Camarillo, CA (US);
Michael De La Cruz, Camarillo, CA (US);
Gregory Flynn, Thousand Oaks, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); C07K 16/00 (2013.01); C12P 21/005 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/41 (2013.01); C12N 2500/02 (2013.01); C12N 2500/32 (2013.01); C12N 2500/34 (2013.01); C12N 2500/38 (2013.01); C12N 2500/74 (2013.01); C12N 2500/76 (2013.01);
Abstract
The present invention relates to methods of modulating (e.g., reducing) the mannose content, particularly high-mannose content of recombinant glycoproteins.