The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9359424 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 07, 2016

Filed:

Jun. 25, 2010
Applicants:

Joel Le Maoult, Melun, FR;

Edgardo Delfino Carosella, Paris, FR;

Inventors:

Joel Le Maoult, Melun, FR;

Edgardo Delfino Carosella, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/74 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70539 (2013.01); A61K 39/001 (2013.01);
Abstract

Multimeric polypeptides and pharmaceutical uses thereof; multimers comprising alpha3 and alpha1 peptides of an HLA-G antigen and methods of producing such multimers, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection. Said multimers comprise at least two monomers, each of said monomers being selected in the group consisting of a peptide P2 of formula P1-X3 or X2-X3, wherein P1 is of formula X1-X2, wherein X1 represents a peptidic linker including a cysteine amino acid and X2 represents an alpha1 domain (or alpha1 peptide) of HLA-G and X3 represents an alpha3 domain of HLA-G.


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Le Maoult, Joel. (2016). Multimeric polypeptides of hla-g including alpha1-alpha3 monomers and pharmaceutical uses thereof (U.S. Patent No. 9359424). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9359424

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