The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Jul. 11, 2014
Applicants:
Aimee Usera, Cambridge, MA (US);
Zachary Robinson, Arlington, MA (US);
Jennifer Cobb, Cambridge, MA (US);
Inventors:
Aimee Usera, Cambridge, MA (US);
Zachary Robinson, Arlington, MA (US);
Jennifer Cobb, Cambridge, MA (US);
Assignee:
NOVARTIS AG, , CH;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/103 (2006.01); A61K 49/00 (2006.01); A61K 47/48 (2006.01); C07K 5/083 (2006.01); C07K 5/062 (2006.01); C07K 1/13 (2006.01); C07D 209/42 (2006.01); C07K 7/02 (2006.01); C07K 5/072 (2006.01); C07C 271/22 (2006.01); C07C 317/28 (2006.01); A61K 38/06 (2006.01); A61K 38/05 (2006.01); A61K 38/07 (2006.01);
U.S. Cl.
CPC ...
C07K 5/101 (2013.01); A61K 47/48261 (2013.01); A61K 49/0002 (2013.01); C07C 271/22 (2013.01); C07C 317/28 (2013.01); C07D 209/42 (2013.01); C07K 1/13 (2013.01); C07K 5/06043 (2013.01); C07K 5/06104 (2013.01); C07K 5/0808 (2013.01); C07K 7/02 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); C07C 2102/24 (2013.01);
Abstract
The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.