The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
Mar. 01, 2011
Applicants:
Kevin D. Shenk, Palo Alto, CA (US);
Francesco Parlati, San Francisco, CA (US);
Mark K. Bennett, Moraga, CA (US);
Inventors:
Kevin D. Shenk, Palo Alto, CA (US);
Francesco Parlati, San Francisco, CA (US);
Mark K. Bennett, Moraga, CA (US);
Assignee:
Onyx Therapeutics, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01); A61P 31/00 (2006.01); A61P 29/00 (2006.01); A61P 3/04 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); A61K 38/06 (2006.01); A61K 38/07 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 5/08 (2006.01); C07D 209/20 (2006.01); C07D 241/24 (2006.01); C07D 295/104 (2006.01); C07D 303/36 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0827 (2013.01); C07D 209/20 (2013.01); C07D 241/24 (2013.01); C07D 295/104 (2013.01); C07D 303/36 (2013.01); C07D 405/12 (2013.01);
Abstract
One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.