The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Feb. 24, 2015
Applicant:

Biolab Sanus Farmacêutica Ltda., Taboão de Serra, BR;

Inventors:

Sérgio Luiz Sacurai, São Paulo, BR;

Carlos Eduardo Da Costa Touzarim, São Paulo, BR;

Fabiano Travanca Toledo, Osasco, BR;

Bruno Artur De Sousa, São Paulo, BR;

Assignee:

BIOLAB SANUS FARMACEUTICA LTDA., Taboao De Serra, BR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 241/38 (2006.01); C07D 498/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention relates to novel derivatives of 6,7-dihydro-3H-oxazolo[3,4-a]pyrazine-5,8-dione represented by formula (I): and a mixture of these derivatives. The present invention also encompasses the pharmaceutical compositions comprising an effective amount of a said compounds, object of the present invention, as well as to the use of the compounds and/or derivatives as a phosphodiesterase enzyme inhibitor, and the use of the compounds and/or derivatives in the treatment of erectile dysfunction, disorders and/or conditions treatable with relaxation of tissues and disorders treatable with phosphodiesterase inhibitors, more particularly PDE-5 inhibitor. A further objective of the present invention is to provide a medication comprising a therapeutically effective amount of said compound and a method of treating using the said novel compounds.


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