The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2016
Filed:
May. 21, 2012
Applicants:
Benjamin Wolozin, Newton, MA (US);
Marcie Glicksman, Winchester, MA (US);
Gregory D. Cuny, Houston, TX (US);
Justin Boyd, Winchester, MA (US);
Inventors:
Benjamin Wolozin, Newton, MA (US);
Marcie Glicksman, Winchester, MA (US);
Gregory D. Cuny, Houston, TX (US);
Justin Boyd, Winchester, MA (US);
Assignees:
AQUINNAH PHARMACEUTICALS, INC., Newton, MA (US);
THE BRIGHAM AND WOMEN'S HOSPITAL, INC., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 207/36 (2006.01); C07D 211/26 (2006.01); C07D 211/52 (2006.01); C07D 215/227 (2006.01); C07D 215/36 (2006.01); C07D 239/52 (2006.01); C07D 239/94 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 417/04 (2006.01); A61P 25/28 (2006.01); A61K 31/4025 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/551 (2006.01); A61K 31/365 (2006.01); A61K 31/704 (2006.01); C07D 211/34 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/365 (2013.01); A61K 31/4025 (2013.01); A61K 31/445 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/551 (2013.01); A61K 31/704 (2013.01); C07D 207/36 (2013.01); C07D 211/34 (2013.01); C07D 211/52 (2013.01); C07D 215/227 (2013.01); C07D 215/36 (2013.01); C07D 239/52 (2013.01); C07D 239/94 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/06 (2013.01); C07D 417/04 (2013.01); G01N 33/5058 (2013.01);
Abstract
Herein, methods of modulating inclusion formation and stress granules in cells are described. The methods comprise contacting a cell with an inclusion inhibitor. Methods for screening for modulators of TDP-43 aggregation are also described.