The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Jul. 13, 2012
Applicants:

Peter Åsberg, Stockholm, SE;

Kristin Hammer, Sollentuna, SE;

Johan Olsson, Stockholm, SE;

Martin Henriksson, Solna, SE;

Inventors:

Peter Åsberg, Stockholm, SE;

Kristin Hammer, Sollentuna, SE;

Johan Olsson, Stockholm, SE;

Martin Henriksson, Solna, SE;

Assignee:

NEUROSCIOS GMBH, St. Radegund/Graz, AT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 261/20 (2006.01); C07D 235/20 (2006.01); C07D 333/18 (2006.01); C07D 409/10 (2006.01); C07D 333/60 (2006.01); C07D 409/14 (2006.01); C07D 409/04 (2006.01); C07D 333/24 (2006.01); C07D 413/10 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 403/10 (2006.01);
U.S. Cl.
CPC ...
C07D 261/20 (2013.01); C07D 235/20 (2013.01); C07D 333/18 (2013.01); C07D 333/24 (2013.01); C07D 333/60 (2013.01); C07D 403/10 (2013.01); C07D 409/04 (2013.01); C07D 409/10 (2013.01); C07D 409/14 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to novel chemical compounds formula (I) (C)—B-(A)-B—(C)(I) wherein m is 0 or 1, and n is independently 0, 1, 2 or 3, A, each B and each C are independently selected from phenylene and five- and six-membered heteroaromatic rings, and for a terminal ring B or C also from bicyclic heteroaromatic fused rings having seven to ten ring members, wherein the bond between at least two of the rings A to C may be replaced by a carbonyl group (—CO—), wherein at least two of the rings A to C are substituted with one or two groups R, and wherein each ring A to C further optionally is substituted with one or two groups R. The compounds are useful in therapy, especially therapy of a mammal suffering from a disease involving misfolded or aggregated forms of proteins.


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