The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Dec. 18, 2012
Applicant:

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Zhuorong Li, Beijing, CN;

Xingyue Ji, Beijing, CN;

Situ Xue, Beijing, CN;

Guanghui Zheng, Beijing, CN;

Yuhuan Li, Beijing, CN;

Peizhen Tao, Beijing, CN;

Jiandong Jiang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/30 (2006.01); C07D 213/68 (2006.01); C07D 213/55 (2006.01); C07D 213/64 (2006.01); C07D 213/65 (2006.01); C07D 213/69 (2006.01); C07C 65/28 (2006.01); C07C 69/92 (2006.01); C07C 51/09 (2006.01); C07C 65/105 (2006.01); C07C 65/19 (2006.01); C07C 43/215 (2006.01); C07C 43/23 (2006.01); C07D 213/80 (2006.01); C07D 311/58 (2006.01); C07C 275/00 (2006.01); C07C 275/54 (2006.01); C07C 279/22 (2006.01); C07C 281/02 (2006.01); C07D 333/16 (2006.01); C07D 333/24 (2006.01); C07D 233/60 (2006.01); C07D 233/90 (2006.01); C07C 217/20 (2006.01); C07C 217/22 (2006.01); C07D 241/04 (2006.01); C07C 229/08 (2006.01); C07C 235/46 (2006.01); C07C 235/62 (2006.01); C07C 235/64 (2006.01); C07D 207/16 (2006.01); C07D 211/58 (2006.01); C07C 69/157 (2006.01); C07C 69/36 (2006.01); C07C 39/21 (2006.01); C07C 51/353 (2006.01); C07C 51/36 (2006.01); C07C 41/18 (2006.01); C07C 67/30 (2006.01); C07C 231/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/30 (2013.01); C07D 213/55 (2013.01); C07D 213/64 (2013.01); C07D 213/65 (2013.01); C07D 213/68 (2013.01); C07D 213/69 (2013.01); C07C 39/21 (2013.01); C07C 41/18 (2013.01); C07C 43/215 (2013.01); C07C 43/23 (2013.01); C07C 51/09 (2013.01); C07C 51/353 (2013.01); C07C 51/36 (2013.01); C07C 65/105 (2013.01); C07C 65/19 (2013.01); C07C 65/28 (2013.01); C07C 67/30 (2013.01); C07C 69/157 (2013.01); C07C 69/36 (2013.01); C07C 69/92 (2013.01); C07C 217/20 (2013.01); C07C 217/22 (2013.01); C07C 229/08 (2013.01); C07C 231/12 (2013.01); C07C 235/46 (2013.01); C07C 235/62 (2013.01); C07C 235/64 (2013.01); C07C 275/00 (2013.01); C07C 275/54 (2013.01); C07C 279/22 (2013.01); C07C 281/02 (2013.01); C07C 2101/02 (2013.01); C07C 2101/14 (2013.01); C07D 207/16 (2013.01); C07D 211/58 (2013.01); C07D 213/80 (2013.01); C07D 233/60 (2013.01); C07D 233/90 (2013.01); C07D 241/04 (2013.01); C07D 311/58 (2013.01); C07D 333/16 (2013.01); C07D 333/24 (2013.01);
Abstract

Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.


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